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[DOI] [PubMed] [Google Scholar] 6.Duim S.N., Vlasveld L.T., Mezger S.T.P., Mingels A.M.A., Ramakers C.R.B., de Boer D., Heil S.G., Nexo E., van Rossum A.P

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Many peptides are cleared from the bloodstream shortly after administration resulting in limited exposure to the brain capillaries, reducing their ability to penetrate the BBB

Common applications include the reconstitution of compatible research materials, laboratory dilution workflows, formulation studies, stability investigations, and general laboratory preparation procedures where a preserved aqueous medium is required

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In 2022, the FDA placed BPC-157 on its list of bulk drug substances that may not be used in compounding under Section 503A, though enforcement actions have varied by jurisdiction [5]